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Human Chorionic Gonadotrophin for Injection

Human Chorionic Gonadotrophin for Injection

[Product Name]

Human Chorionic Gonadotrophin for Injection

[Composition]

A preparation of Chorionic Gonadotrophin, which is a sterile lyophilized form after adding appropriate excipient. The titer is 80%-125% of the labelled amount.

[Indication]

A. The diagnosis and treatment of puberty cryptorchidism.

B. Male infertility induced by pituitary dysfunction. It can be combined with HMG. Long-term gonadotropin dysfunction should be supplemented with testosterone.

C. Female anovulatory infertility induced by pituitary gonadotropin deficiency. It is often treated after clomiphene treatment is ineffective. The combined use with menotropin and post-menopausal gonadotropin could promote ovulation.

D. It is used for obtaining multiple oocytes in vitro fertilization and should combine with postmenopausal gonadotropin.

E. Female luteal phase defect.

F. Dysfunctional uterine bleeding, threatened abortion during early pregnancy, habitual abortion.

[Dosage and Administration]

For adult:

A. For gonadal dysfunction caused by male gonadotropin dysfunction, inject intramuscularly 1000-4000 units, twice or 3 times per week lasting for weeks or months. To promote sperm production, treatment should be continued for 6 months or more. If the sperm count is less than 5,000,000 / ml, the application should be combined with HMG for 12 months.

B. Ovulation promotion. For anovulatory female infertility or in vitro fertilization, inject intramuscularly 5000-10000 IU one day after the last treatment of gonadotropin of post-menopause or 5 to 7 days after treatment of Clomiphene for consistent 3-6 treatment cycles. If no effect is shown, the drug should be withdrawal.

C. For luteal function defect, inject 1500 IU at 15 to 17 days after ovulation once every other day, for 5 times. The dose can be adjusted according to patients’ response. After pregnancy, the original dose should maintain for 7 to 10 gestational weeks.

D. For functional uterine bleeding. Inject intramuscularly 1000-3000 IU. For habitual abortion and pregnancy threatened abortion, inject 1000-5000 IU intramuscularly.

For children:

A. For determination of slow development of testicular function, inject intramuscularly 2000 IU, once a day, for 3 days.

B. For puberty cryptorchidism, inject intramuscularly 1000-5000 IU, 2-3 times per week. The drug withdraws once beneficial effects show. The total number of injections is not more than 10 times.

[How Supplied]

Packing material: injection vial + Medicinal halogenating butyl rubber plug; ampoule;

Pack: (1)1000 IU, 10 vials/box;

         (2)2000 IU, 10 vials/box;

         (3)5000 IU, 1 vial/ box (1 vial+2 ml sodium chloride injection)

[Storage Condition]

Protect from light and keep tightly sealed in a cool place (store below 20℃).

[Shelf Life]

24 months

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