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Lizhu Pharmaceutical Group, Health Yuan Pharmaceutical Group, and Zhihua Technology have initiated a strategic partnership to collaboratively advance the application of AI in process chemistry.


Release time:

2021-08-03

In June 2021, ZhiHua Technology (Chemical.AI), a research and development technology company empowered by AI, announced a strategic partnership with Lijun Pharmaceutical Group and Health Yuan Pharmaceutical Group, which are dedicated to discovering and supporting the research and development of leading pharmaceutical innovation technologies and products in China. The three parties will leverage their respective strengths, including ZhiHua Technology's advanced computer-aided retro-synthesis route design system, along with the expertise and experience of process chemistry specialists from Lijun Pharmaceutical and Health Yuan Pharmaceutical, to develop process chemistry modules and enhance the research and development of process chemistry through AI retro-synthesis technology.

Process chemistry plays a crucial role in the later stages of drug development until market launch. The route for drug chemists to synthesize small quantities of compounds in the laboratory is merely a starting point. The industrialization and commercialization of pharmaceutical process chemistry must meet a series of stringent requirements, including green chemistry, production safety, controllable costs, high feasibility of operational routes, and clear patent scope, which necessitates pharmaceutical companies to conduct time-consuming and labor-intensive research. After years of development, ZhiHua Technology's AI retro-synthesis platform has successfully achieved commercialization, actively enhancing efficiency in the field of drug chemistry research and development. Lijun Pharmaceutical and Health Yuan Pharmaceutical Group possess extensive expert knowledge and experience in various drug synthesis and process chemistry, which can be integrated with real-world case studies and data to support and guide the development of the AI retro-synthesis platform in process research and development. The three parties are expected to further empower process chemistry through the AI technology platform, improve industrial output efficiency, and accelerate the pace of drug development.

Dr. Xia Ning, founder and CEO of ZhiHua Technology (Chemical.AI), stated: "Artificial intelligence will bring new development potential and opportunities to China's pharmaceutical industry. By empowering drug development with AI, we can effectively enhance efficiency and reduce costs at various stages of pharmaceutical research and development. We are very pleased to collaborate with Lijun Pharmaceutical and Health Yuan Pharmaceutical to leverage our respective advantages, jointly address the challenges and pain points in the new drug development process, and accelerate the application of AI retro-synthesis in the field of process chemistry for mutual benefit and cooperation."

Dr. Liu Jianing, Chief Investment Officer of Lijun Pharmaceutical Group, stated: "In drug development, research on chemical processes is a critical link in the transformation of drugs from the laboratory to industrial production, and it is an essential task for pharmaceutical companies to clarify the drug's properties and the feasibility of industrial scaling. Lijun Pharmaceutical Group, along with its parent company Health Yuan Pharmaceutical Group, is pleased to engage in deep cooperation with ZhiHua Technology to promote the application of AI technology in the development of green, safe, and efficient chemical synthesis processes."

About Chemical.AI

        Chemical.AI is a research and development technology company empowered by AI, utilizing artificial intelligence technology, chemical big data, and machine learning to develop tools that significantly improve the efficiency of chemical research. It is committed to creating an intelligent compound planning platform to shape the future of chemistry.

        Chemical.AI was established in 2018 in Wuhan and has a subsidiary in Shanghai. The team consists of experts in cheminformatics, chemical synthesis, and outstanding IT talents. Currently, Chemical.AI has successfully provided technical services to many well-known domestic and foreign pharmaceutical companies and CROs, engaging in deep cooperation in areas such as synthetic route and process route design.

—— Reprinted from the "Chemical.AI WeChat Official Account"

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